Shope fibroma

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Shope fi·bro·ma

a connective tissue tumor of cottontail rabbits caused by a poxvirus of the genus Leporipoxvirus and found by Shope to be transmissible with cellular suspensions or Berkefeld filtrates; it is related to myxomatosis and is used in Europe as a source of vaccine to protect against the myxoma virus.
Synonym(s): rabbit fibroma


Richard E., U.S. pathologist, 1902-1966.
Shope fibroma - a connective tissue tumor of cottontail rabbits caused by a poxvirus of the genus Leporipoxvirus. Synonym(s): rabbit fibroma
Shope fibroma virus - a poxvirus of the genus Leporipoxvirus, closely related to vaccinia and myxoma viruses, that causes Shope fibroma. Synonym(s): rabbit fibroma virus
Shope papilloma - a papillomatous growth found in wild cottontail rabbits.
Shope papilloma virus - a papillomavirus infecting wild cottontail rabbits.


named after R. E. Shope, American virologist.

Shope fibroma
see Shope rabbit fibroma.
Shope papilloma
caused by a papilloma virus and manifested by gray to black, tall, thin, horny structures on the skin of wild rabbits. The lesions may be on the head, neck, shoulders, abdomen and inside the thighs. The disease is transmissible.
References in periodicals archive ?
Shope fibroma virus (SFV) was first used as a vaccine (6,7) but was only moderately effective.
Myxoma virus and Shope fibroma virus encode dual-specificity tyrosine/serine phosphatases which are essential for virus viability.
Tumorigenic poxviruses: genomic organization of malignant rabbit virus, a recombinant between Shope fibroma virus and myxoma virus.