In ESTSCLE, less than 50% of the total tumor mass is composed of structural areas resembling sex cords and the tumor behavior is malignant in around 15% of cases [4, 5].
Ugurluoglu, and C Celik, "Uterine tumour resembling ovarian sex cord tumour- A rare entity," Journal of Clinical and Diagnostic Research, vol.
Schmidt, "Uterine tumors resembling ovarian sex cord tumors treatment, recurrence, pregnancy and brief review," Gynecologic Oncology Reports, vol.
On day 11, gonadal function was first noticed by sex cord
Clumps of mesenchymal cells between the sex cords will become vascularized and give rise to Leydig cells.
In the absence of the Y chromosome, the primitive sex cords remain disorganized and eventually degrade in the medullary region.
The organization of sex cords and appearance of Sertoli cells in males occurs much earlier than formation of primordial follicles in females.
I begin with the tumors that, in some cases at least, are the most simple in this overall category, the stromal tumors (Figure 1), before addressing issues related to those of pure sex cord and then mixed sex cord and stromal type, a more microscopically heterogeneous group of neoplasms.
Indeed, Dr Scully's collection of sex cord tumors, which must be larger than any other existent that I am aware of, contains at most 2 or 3 examples of this very rare neoplasm.
Granulosa cell tumor (Fig 3) was the commonest sex cord - stromal tumor (4/7, 57.14%).
DISCUSSION: Sexcord Stromal Tumors: Sex cord-stromal tumors are ovarian tumors that are believed to originate in theca cells, other stromal cells, granulosa cells and their testicular sex cord counterparts, the Sertoli and Leydig cells.
Mutational analysis (c.402C>G) of the FOXL2 gene and immunohistochemical expression of the FOXL2 protein in testicular adult type granulosa cell tumors and incompletely differentiated sex cord