ferritin

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ferritin

 [fer´ĭ-tin]
the complex of iron and apoferritin, a major form in which iron is stored in the body.

fer·ri·tin

(fer'i-tin),
An iron-protein complex, containing up to 23% iron, formed by the union of ferric ions with apoferritin; it is found in the intestinal mucosa, spleen, bone marrow, reticulocytes, and liver, and regulates iron storage and transport from the intestinal lumen to plasma.
See also: apoferritin.

ferritin

/fer·ri·tin/ (-ĭ-tin) the iron-apoferritin complex, one of the chief forms in which iron is stored in the body.

ferritin

(fĕr′ĭ-tĭn)
n.
An iron-containing protein complex, found principally in the intestinal mucosa, spleen, and liver, that functions as the primary form of iron storage in the body.

ferritin

[fer′itin]
Etymology: L, ferrum, iron
an iron compound formed in the intestine and stored in the liver, spleen, and bone marrow for eventual incorporation into hemoglobin. Serum ferritin levels are used as an indicator of the body's iron stores. Normal adult blood levels are 12 to 300 ng/mL for males and 10 to 150 ng/mL for females.

ferritin

Hematology A major iron storage protein present in small amounts in serum; in healthy adults, serum ferritin reflects the body's iron store, and can be used to detect iron deficiency Ref range ♂ 33-236 ng/mL; ♀, < 40 yrs 12-263 ng/mL; > 40 yrs 11-122 ng/mL; ↓ Ferritin Hypochromic anemia, microcytic anemia. iron deficiency anemia↑ Ferritin Iron overload, hemochromatosis, inflammation, malignancy

fer·ri·tin

(fer'i-tin)
An iron protein complex, containing up to 23% iron, formed by the union of ferric iron with apoferritin; it is found in the intestinal mucosa, spleen, bone marrow, reticulocytes, and liver, and regulates iron storage and transport from the intestinal lumen to plasma.

ferritin

The principal IRON-binding protein of the body. Ferritin acts as an iron store in the liver and other tissues. Each ferritin molecule can hold up to 4500 iron atoms and the amount of iron in ferritin molecules accurately reflects the total iron stores of the body. Ferritin also protects against the toxic effects of excess iron.

ferritin

a conjugated, electron-dense protein concerned in the absorption of iron through the intestinal mucosa. It serves as a storage protein for iron in the liver and spleen.

Ferritin

A protein found in the liver, spleen, and bone marrow that stores iron.
Mentioned in: Iron Tests

ferritin

an iron-protein complex, which acts as a store for iron. Found mainly in the liver but also in the spleen and bone marrow. Serum ferritin measurement is used as a marker of total body iron. See also anaemia.

ferritin

water-soluble iron-protein complex, used in haemoglobin formation

fer·ri·tin

(fer'i-tin)
An iron protein complex, containing up to 23% iron, formed by the union of ferric iron with apoferritin; it is found in the intestinal mucosa, spleen, bone marrow, reticulocytes, and liver.

ferritin (fer´itin),

n the compound iron-appoferritin, which is produced in the intestine and stored primarily in the liver, spleen, and bone marrow. It eventually becomes a component of hemoglobin and can be measured to estimate the body's iron levels.

ferritin

the iron-apoferritin complex, one of the forms in which iron is stored in the body.

Patient discussion about ferritin

Q. My Iron/TIBC tests normal, Ferritin,Serum = 22. Range 22-322. What is the problem? Iron Bind. Cap. ug/dL 324 range 250 - 450 UIBC ug/dL 206 range 150 - 375 Iron, Serum ug/dL 118 range 40 - 155 Iron Saturation % 36 range 15 - 55 Biopsy = Prostate Cancer....PCA high = 10.2 PSA now 8.3 PSA Ultra W/Serial Monitor ...Ultrasenitive = 8.26

A. What makes you think something is not normal? Ferritin values may be low in some people, and iron deficiency is usually defined as ferritin 15. Do you have anemia? Currently, it doesn't seem you have any problem with the iron levels.

Take care,

More discussions about ferritin
References in periodicals archive ?
In patients Exjade lowered the levels of iron in the blood (measured by serum ferritin levels) and liver (measured by liver iron concentration).
4 g/dL Serum ferritin 116 ng/mL 189 ng/mL Unchanged overtime Note: Based on data from a phase II, double-blind trial involving 141 subjects.
Moreover, those with COMBI anemia present with a normocytic and normochromic (or occasionally microcytic, hypochromic) blood picture, and this type of anemia is characterized by reduced serum iron levels, reduced/normal serum ferritin levels, elevated/normal TIBC, elevated/normal serum transferrin concentrations and relative EPO deficiency.
Lewis' presentation confirmed that Zerenex met the pre-defined primary and key secondary endpoints, highlighting that Zerenex is an efficacious and safe oral phosphate binder that controls serum phosphorus, increases iron stores as measured by serum ferritin and TSAT, and reduces the use of IV iron and ESAs, while sustaining hemoglobin as compared to the active control group.
2011) Urinary hepcidin identifies a serum ferritin cut-off for iron supplementation in young athletes: a pilot study.
Under-recognition of the prevalence and importance of preoperative iron deficiency is likely to have contributed to the lack of serum ferritin or iron studies in our cohort.
Blood hemoglobin (Hb), serum ferritin and serum transferrin were also measured in all subjects before and following each intervention.
These patients typically have normal or high serum ferritin levels but low transferrin saturation and require parenteral iron infusions.
An elevated serum ferritin level, the most widely used surrogate marker of iron stores, has been associated with an adverse outcome for HSCT patients.