Sertoli cells


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Related to Sertoli cells: Leydig cells, Leydig

Ser·to·li cells

(sĕr-tō'lē),
elongated cells in the seminiferous tubules that ensheathe spermatogenic cells, providing a microenvironment that supports spermiogenesis and spermatocytogenesis; they secrete androgen-binding protein and establish the blood-testis barrier by forming tight junctions with adjacent Sertoli cells.
Synonym(s): nurse cells

Ser·to·li cells

(ser-tō'lē selz)
Elongated cells in the seminiferous tubules that ensheathe spermatids, providing a microenvironment that supports spermiogenesis; they secrete androgen-binding protein and establish the blood-testis barrier by forming tight junctions with adjacent Sertoli cells.

Sertoli cells

Elongated cells in the walls of the seminiferous tubules that closely surround (‘nurse’) the spermatids, encouraging spermatogenesis. Together, they provide a blood-testis barrier and secrete an androgen-binding protein. (Enrico Sertoli, Italian histologist, 1842–1910).

Sertoli cells

or

nurse cells

large nutritive cells occurring in the wall of SEMINIFEROUS TUBULES that serve to nourish the developing sperm. They are named after the Italian histologist, E. Sertoli.

Sertoli,

Enrico, Italian histologist, 1842-1910.
Sertoli cell tumor - a testicular tumor. Synonym(s): androblastoma
Sertoli cells - elongated cells in the seminiferous tubules to which spermatids are attached during spermiogenesis. Synonym(s): nurse cells
Sertoli columns
Sertoli-cell-only syndrome - the absence from the seminiferous tubules of the testes of germinal epithelium, Sertoli cells alone being present. Synonym(s): Del Castillo syndrome
References in periodicals archive ?
Aquaporin-4 as a molecular partner of cystic fibrosis transmembrane conductance regulator in rat Sertoli cells.
Large cell calcifying Sertoli cell tumor of the testis: contrasting features of six malignant and six benign tumors and a review of the literature.
Development of Sertoli cells during mini-puberty in normal and cryptochid testes.
In fact, when the embryonic Sertoli-like cells were used to sustain other cells in a Petri dish, Buganim noted that the cells supported by the trans-differentiated cells thrived, living longer than cells sustained by actual native Sertoli cells.
Postnatal testis development, sertoli cell proliferation and number of different spermatogonial types in C57BL/6J mice made transiently hypo- and hyperthyroidic during the neonatal period.
Treatment Sertoli Cells (days) 30 Days 60 Days Control 3.
Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse.
Rather, it is the amount of the SMAD3 protein in the Sertoli cell that is different in the immature, multiplying Sertoli cell compared to the mature, adult cell," said the researchers.
The testes contain three different types of cells namely Leydig cells responsible for production of testosterone, spermatogonia responsible for spermatogenesis (sperm cells) and Sertoli cells responsible for secretion of androgen binding protein, inhibin, sulfated glycoprotein-2 and transferrin.
The frequency of reported Y chromosome microdeletions varies from 1 per cent in a cohort of men undergoing intracytoplasmic sperm injection (ICSI) for varying reasons (3) to 55 per cent in men with Sertoli cell only (SCO) syndrome (4).
Saneron is committed to providing readily available, non-controversial stem cells for cellular therapies and has patented and patent-pending technology relating to our platform technology of umbilical cord blood and Sertoli cells.