Sertoli cells


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Related to Sertoli cells: Leydig cells, Leydig

Ser·to·li cells

(sĕr-tō'lē),
elongated cells in the seminiferous tubules that ensheathe spermatogenic cells, providing a microenvironment that supports spermiogenesis and spermatocytogenesis; they secrete androgen-binding protein and establish the blood-testis barrier by forming tight junctions with adjacent Sertoli cells.
Synonym(s): nurse cells

Ser·to·li cells

(ser-tō'lē selz)
Elongated cells in the seminiferous tubules that ensheathe spermatids, providing a microenvironment that supports spermiogenesis; they secrete androgen-binding protein and establish the blood-testis barrier by forming tight junctions with adjacent Sertoli cells.

Sertoli cells

Elongated cells in the walls of the seminiferous tubules that closely surround (‘nurse’) the spermatids, encouraging spermatogenesis. Together, they provide a blood-testis barrier and secrete an androgen-binding protein. (Enrico Sertoli, Italian histologist, 1842–1910).

Sertoli cells

or

nurse cells

large nutritive cells occurring in the wall of SEMINIFEROUS TUBULES that serve to nourish the developing sperm. They are named after the Italian histologist, E. Sertoli.

Sertoli,

Enrico, Italian histologist, 1842-1910.
Sertoli cell tumor - a testicular tumor. Synonym(s): androblastoma
Sertoli cells - elongated cells in the seminiferous tubules to which spermatids are attached during spermiogenesis. Synonym(s): nurse cells
Sertoli columns
Sertoli-cell-only syndrome - the absence from the seminiferous tubules of the testes of germinal epithelium, Sertoli cells alone being present. Synonym(s): Del Castillo syndrome
References in periodicals archive ?
Neonatal exposure of male rats to bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis.
Malignant Sertoli cell tumors of the testis: a study of 13 examples of a neoplasm frequently misinterpreted as seminoma.
Rather, it is the amount of the SMAD3 protein in the Sertoli cell that is different in the immature, multiplying Sertoli cell compared to the mature, adult cell," said the researchers.
The testes contain three different types of cells namely Leydig cells responsible for production of testosterone, spermatogonia responsible for spermatogenesis (sperm cells) and Sertoli cells responsible for secretion of androgen binding protein, inhibin, sulfated glycoprotein-2 and transferrin.
Presence of xenobiotics, defect in the cellular mechanism that regulates free radical generation, spermatozoa with defective cytoplasmic extrusion, varicocele, defect in Sertoli cell that removes residual cytoplasm of spermatozoa (48) are proposed to be the main causes for origin of oxidative stress.
Producing sertoli cells from bone marrow, as well as sperm, is another avenue being explored.
The proband in this family suffered from another rare illness, ie, Sertoli cell only syndrome.
Fine estructure of Sertoli cells in three marine snails with a discussion on the functional morphology of Sertoli cells in general.
The process of spermatogenesis depends on somatic testicular Leydig cells and Sertoli cells that control germ cell development (Sharpe et al.
1980) showed that in the atheriniform Fundulus grandis the efferent duct wall cells derive from Sertoli cells.
Advanced germ cells including spermatids and Sertoli cells in some tubules were immunoreactive against anti-galectin-3.