Mohanty, "Seronegative spondarthritis and human leucocyte antigen association," British Journal of Biomedical Science, vol.
Mohanty, "Novel HLA B*2714 and B*2708 allele associations in seronegative spondarthritis patients and haemophilia patients with chronic synovitis in India," Tissue Antigens, vol.
The latter describes his first encounter with Behcet's in his Istanbul internal medicine and rheumatology practice since its identification there decades ago by its namesake, and introduces the debates over its nature as an autoimmune disease or seronegative spondarthritis
. International contributors discuss its historical description, clinical features, differential diagnosis (e.g., from inflammatory bowel disease), epidemiology, and treatment.
The fact of the matter is that there are elements of Behcet's that go along with seronegative spondarthritis. There surely are immunological aberrations in Behcet's; the unique pathergy phenomenon of Behcet's represents a bona fide increased inflammatory propensity, and there can be vasculitis in this curious condition from the minute venule all the way to the left ventricle.
(10) After all these years, I now reason that had we considered that there might have been some elements that could have been common to the other diseases in the seronegative spondarthritis "lump," our debate would have taken a more fruitful course.
Several types of connective tissue disease are also addressed, as is seronegative spondarthritis
. Editor Madhok is affiliated with the Center for Rheumatic Diseases at Glasgow Royal Infirmary NHS Trust in the UK.