ST14

(redirected from Serine protease 14)

ST14

A gene on chromosome 11q24-q25 that encodes matriptase, a type-II transmembrane serine protease which degrades extracellular matrix and is thought to play a role in breast cancer invasion and metastasis.

Molecular pathology
Defects in ST14 cause ichthyosis with hypotrichosis, autosomal recessive.
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