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For the purpose of this study, 677 patients with 2 consecutive serial measurements obtained 3 months apart (hereinafter referred to as first-quarter and second-quarter measurements, respectively) were included in final analyses.
These findings "raise the possibility that serial measurements of troponin concentration may improve its prognostic value, and that persistently elevated and increasing troponin concentrations may be the best predictor of adverse outcomes," said Dr.
A cancer risk algorithm using serial measurements of serum cancer antigen 125 (CA-125) detected more cases of ovarian cancer than did a single-threshold rule, according to a large, prospective screening study published in the Journal of Clinical Oncology.
2] Recent rationalisation of biomarker investigation has occurred, with serial measurements of troponins using highly sensitive assays being advised while other biomarkers such as creatine kinase (CK) or myoglobin are no longer indicated, given the limited evidence of their additional benefit.
Serial measurements can be used to titrate GDMT to optimal doses.
A prospective cohort study found that serial measurements of troponin increased the diagnostic sensitivity for AMI.
Serial measurements also revealed an inverse relationship between changes in testosterone levels and insulin resistance.
A tool for comparison of different and more complicated algorithms applied to serial measurements is computer simulation (e.
This study indicates that serial measurements of cholinesterase activity across an agricultural season can detect exposure to pesticides among farmworkers.
Professor Fall said: "This study, in which the children have had high-quality serial measurements of growth, biochemistry and body composition, will fill many of the gaps left by other birth cohort studies.
5 [micro]g/l, but it is important to perform serial measurements.