Serenoa repens


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Related to Serenoa repens: Pygeum africanum

saw palmetto

,

American Dwarf Palm Tree

(trade name),

Cabbage Palm

(trade name),

Ju-Zhong

(trade name),

Palmier Nain

(trade name),

Sabal

(trade name),

Sabal Fructus

(trade name),

Saw Palmetto Berry

(trade name),

Serenoa repens

(trade name)

Classification

Therapeutic: benign prostatic hyperplasia bph agents
Benign prostatic hyperplasia

Action

Exerts antiandrogenic, anti-inflammatory and antiproliferative properties in prostate tissue resulting in improvement in BPH symptoms such as frequent urination, hesitancy, urgency and nocturia.
Comparable in efficacy to finasteride but may be less effective than prazosin.

Therapeutic effects

Decreased urinary symptoms of BPH.

Pharmacokinetics

Absorption: Unknown.
Distribution: Unknown.
Metabolism and Excretion: Unknown.
Half-life: Unknown.

Time/action profile

ROUTEONSETPEAKDURATION
PO1–2 mosunknown48 wk (longest studied treatment duration)

Contraindications/Precautions

Contraindicated in: Pregnancy and lactation.
Use Cautiously in: Prior to surgery (discontinue 2 weeks before to prevent bleeding).

Adverse Reactions/Side Effects

Central nervous system

  • dizziness
  • headache

Gastrointestinal

  • nausea
  • vomiting
  • constipation and diarrhea

Interactions

Hormonal action may interfere with other hormonal therapies (testosterone, hormonal contraceptives ).Avoid use with antiplatelet or anticoagulant drugs (may ↑ bleeding risk).Concomitant use with herbs that affect platelet aggregation such as ginger, garlic, gingko, and ginseng may ↑ bleeding risk.
Oral (Adults) Lipophilic extract (80–90% fatty acids)—160 mg twice daily or 320 mg once daliy. Whole berries—1–2 grams daily. Liquid extract from berry pulp—1–2 mL three times daily. Tea (efficacy is questionable due to lipophilicity of active constituents)—1 cup three times daily. Tea is prepared by steeping 0.5–1 gram dried berry in 150 mL boiling water for 5–10 minutes.

Availability

Lipophilic extract (80-90% fatty acids): OTC
Whole berries: OTC
Liquid extract: OTC

Nursing implications

Nursing assessment

  • Assess patient for symptoms of benign prostatic hypertrophy (BPH) (urinary hesitancy, feeling of incomplete bladder emptying, interruption in urinary stream, impairment in size and force of urinary stream, terminal urinary dribbling, straining to start flow, dysuria, urgency) before and periodically during therapy.
  • Rectal exams prior to and periodically throughout therapy to assess prostate size are recommended.

Potential Nursing Diagnoses

Impaired urinary elimination (Indications)
Deficient knowledge, related to medication regimen (Patient/Family Teaching)

Implementation

  • Take on a full stomach to minimize GI effects.

Patient/Family Teaching

  • Advise patients to start therapy with this herbal supplement only after evaluation by a health care professional who will provide continued follow up care.
  • Inform patients that saw palmetto does not alter the size of the prostate but still should relieve the symptoms associated with BPH.
  • Tell patients that taking this herbal supplement with food should reduce the GI effects and make it easier to tolerate.

Evaluation/Desired Outcomes

  • Decrease in urinary symptoms of BPH.
References in periodicals archive ?
Antibiotics Quinolones, trimethoprim, tetracyclines, macrolides, [beta]-lactam antibiotics NSAIDs Salicylates, profens, sulfonanilides Steroidal anti-inflammatory Docosanoic acid (DHA), eicosanoid acid drugs (EPA) Fibrinolytic treatment Serratiopeptidase, bromelain, escin Antioxidants Superoxide dismutases, catalase, glutathione peroxidase, glutathione, N-acetyl-cysteine, vitamin A, vitamin C (ascorbic acid), vitamin E, coenzyme Q10, carnitine, myoinositol, lycopene, astaxanthin, Serenoa repens Micronutrients Selenium, zinc, copper Table 3: Other antioxidants.
densa (needles only South Florida Slash Pine within plots) Polygonella myriophylla Woody Wireweed Quercus chapmanii Chapman's Oak Quercus geminata Sand Live Oak Quercus inopina Scrub Oak Sabel etonia Scrub Palmetto Serenoa repens Saw Palmetto Vaccinium darrowi Darrow's Blueberry Vaccinium myrsinites Shiny Blueberry Table 2.--Vegetation characteristics measured prior to burn, adjusted from Brown's Downed Woody Fuels inventory Vegetation variable Description litter depth (cm) Average litter depth from center of plot quarters.
El palmito salvaje (Serenoa repens) ha sido aprobado enAlemania para el tratamiento de la HPB, mientras que en Italia el 50% de los hombres con sintomas urinarios lo utilizan (3, 4).
General logistic regression models to predict flowering of Serenoa repens and Sabal etonia in response to fire.
Most of the specimens with host data came from Sabal palmetto, but there is also one record from Serenoa repens (Bartr.) Small (Citrus County, Inverness, 31-VIII-2011, Thomson Paris, hand collection, FSCA# E2011-6243).
Serenoa Repens, Lycopene and Selenium: A Triple Therapeutic Approach to Manage Benign Prostatic Hyperplasia.
Chicago, IL-based SymphonyIRI determined that the top-selling single herbs of 2012 in the FDM channel were: cranberry (Vaccinium macrocarpon), garlic (Allium sativum), saw palmetto (Serenoa repens), soy (Glycine max) and ginkgo (Ginkgo biloba) leaf extract.
Evidence that Serenoa repens extract displays an antioestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients.
Saw palmetto (Serenoa repens) has been used by more than 2 million men in the United States.
Pytel, et al., "Long-term Clinical and Biologic Effects of the Lipidosterolic Extract of Serenoa repens in Patients with Symptomatic Benign Prostatic Hyperplasia," Adv.
There is clinical evidence that several prescriptions of herbal medications such as permixon[R] (from Serenoa repens) and tadenan[R] (from Pygeum africanum) improve lower urinary tract function, although the mechanisms of action are not fully understood (Carraro et al., 1996; Levin and Das, 2000).