pulmonary sequestration

(redirected from Sequestration of lung)

sequestration

[se″kwes-tra´shun]

1. abnormal separation of a part from a whole, as a portion of a bone by a pathologic process, or a portion of the circulating blood in a specific part occurring naturally or produced by application of a tourniquet.

2. isolation of a patient.

pulmonary sequestration loss of connection of lung tissue, and sometimes bronchi, with the bronchial tree and pulmonary veins, the tissue receiving its arterial supply from the systemic circulation. It may be completely separated anatomically and physiologically from normally connected lung (extralobar) or contiguous to and partly surrounded by normal lung (intralobar). Called also accessory lung.

pulmonary sequestration

An uncommon–1:1000 adult lobectomy specimens congenital anomaly characterized by misplaced lung parenchyma, which lacks normal communication with the main tracheobronchial tree that may be intralobar or extralobar

Pulmonary sequestration

Intralobar Extralobar

Separate pleura No Yes

Location Posterior basilar Above or below diaphragm

Age of onset 50% > 20 years 60% < one year

Symptoms Recurrent pneumonia Respiratory distress

Laterality 60% left 90% left

♂:♀ ratio 1:1 4:1

Other defects Uncommon > 50%, eg diaphragmatic

defects, tuberous sclerosis

Bronchial
communication Uncommon, small None

Arterial supply Systemic; single aorta Systemic; multiple, small

Venous drainage Inferior pulmonary Systemic; azygous and
vein hemiazygous vein

pulmonary sequestration

A nonfunctioning area of the lung that receives its blood supply from the systemic circulation.