citalopram(redirected from Sepram)
Also found in: Dictionary.
1. an antidepressant compound used in the treatment of major depressive disorder, administered orally as the hydrobromide.
A drug of the SSRI class, C20H21FN2O, used in its hydrobromide form to treat depression.
an antidepressant in the selective serotonin-reuptake inhibitor class.
indication It is used to treat major depressive disorder.
contraindications Known hypersensitivity to this drug prohibits its use. It should not be used with MAO inhibitors. It interacts with several forms of cytochrome P450 and therefore influences many other drugs.
adverse effects Life-threatening effects include convulsions, hemorrhage, first-degree atrioventricular block, and myocardial infarction. Other serious adverse effects include hallucinations, delusions, psychosis, vomiting, asthma, hyperventilation, respiratory infection, dyspnea, bronchitis, pneumonia, angina pectoris, hypertension, palpitations, tachycardia, bradycardia, thrombophlebitis, arthritis, amenorrhea, cystitis, urine retention, and viral infection. Common side effects are numerous, affecting the GI, integumentary, respiratory, cardiovascular, genitourinary, and central nervous systems. Some are also systemic.