Sendai virus


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Sen·dai vi·rus

a parainfluenza virus type 1 reported to cause inapparent infection in many animals; also used extensively to effect fusion of tissue culture cells.

Sendai virus

n.
A paramyxovirus that causes respiratory tract infections in mice, rats, and other mammals, used in the laboratory to induce the formation of hybridoma cells that produce monoclonal antibodies.

Sendai virus

a paramyxovirus that causes a highly contagious disease of the respiratory tract of mice. It also affects rats but is usually subclinical in that species. The syndrome is one of pneumonia with dyspnea and a high mortality rate in young mice.
References in periodicals archive ?
Susceptibility of inbred and outbred mouse strains to Sendai virus and prevalence of infection in laboratory rodents.
Although tissue must be removed when the colloidal gold technique is used, the scientists are now evaluating another marker that is already being used in clinical imaging techniques and that might be engulfed by reforming Sendai virus envelopes -- thus providing a way to follow grafts in vivo.
Sendai virus enables delivery of genes into a host cell without permanently altering the cell's chromosome, which is critical for stem cell therapies.
This has led to a collaborative development of a Sendai virus vector-based AIDS vaccine candidate, which is expected to enter Phase I testing in humans in two to three years.
Jianfeng Lu, Zhang's postdoctoral research associate, removed skin cells from monkeys and people, and exposed them to Sendai virus for 24 hours.
First, the Sendai virus, a kind of cold virus, is considered safe because it does not enter the cell's DNA, and it is killed by heat within 24 hours.
Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells.
Mapping of antigenic domains of Sendai virus nucleocapsid protein expressed in Escherichia coli.
In addition, pIgA, as opposed to IgG or monomeric IgA, neutralizes virus intracellularly, as first was shown with Sendai virus (24).
Parsimony analyses (12) with Sendai virus as outgroup placed PWMV in the cetacean morbillivirus clade with PMV and DMV, with moderate-to-high bootstrap values (N sequence = 70; P sequence = 100).