thiosemicarbazone

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thi·o·sem·i·car·ba·zone

(thī'ō-sem'ē-kar'bă-zōn),
1. A compound containing the thiosemicarbazide radical, =N-NH-C(S)-NH2.
2. One of a group of tuberculostatic drugs that includes thiosemicarbazide, benzaldehyde thiosemicarbazone, and 4-aminoacetylbenzaldehyde thiosemicarbazone.
References in periodicals archive ?
2](VI) complexes of 4-[N-(3:4-methylene dioxy benzylidene) amino] antipyrine semicarbazone ([C.
2] (VI) complexes of 4-[N-3:4-methylene dioxy benzylidene) amino] antipyrine semicarbazone ([C.
Electronic spectra of isothiocyanato and sulphato complexes of semicarbazones and thiosemicarbazones indicate octahedral geometry.
Carbamate (3a), amides (8b), (8d), and (8g) exhibited high activity against all the tested microorganisms, semicarbazone (6d) was completely inactive.
Sequential hydrazinolysis of carbamate (3e) and condensation with a variety of aldehydes and ketones (5a-d) afforded the corresponding semicarbazones (6a-d).
General procedures for synthesis of semicarbazones (6a-d)
This semicarbazide was a good candidate to prepare novel semicarbazones (6a-d) incorporating thiazole ring by condensation with different aldehydes and ketones (5a-d) namely, p-chlorobenzaldehyde, p-hydroxybenzaldehyde, cyclopentanone and cycloheptanone in ethanol containing catalytic amount of glacial acetic acid Scheme-1.
A simple and general method has been developed for the synthesis of various Schiff bases (oximes, hydrazones, semicarbazones and thiosemicarbazones) derived from 5-acyl-1,2,4- triazines.
Keywords: Oximes of 5-acyl-1,2,4-triazines, Hydrazones of 5-acyl-1,2,4-triazines, Thiosemicarbazones and Semicarbazones of 5-acyl-1,2,4-triazines, Antiviral activity, Schiff base.
A series of new Schiff bases (oximes, hydrazones, semicarbazones and thiosemicarbazones) derived from 5-acyl-1,2,4-triazines were synthesized in order to evaluate their biological activities.