PSA

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PSA

Abbreviation for prostate-specific antigen.
Farlex Partner Medical Dictionary © Farlex 2012

PSA

abbr.
1. prostate-specific antigen
2. public service announcement
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

PSA

Prostate-specific antigen. A 34-kD glycoprotein serine protease (formally, kallikrein-related peptidase 3) encoded by KLK3 on chromosome 19q13.41, which has significant homology with other neutral proteases. It is secreted exclusively by the prostate epithelium and is responsible for lysing the seminal coagulum; it is present in the serum and is increased in patients with both benign (acute inflammation and BPH) and malignant (cancer) prostate lesions;. Most serum PSA is bound to protease inhibitors, including alpha1-antichymotrypin (the form usually measured in the lab), alpha1-macroglobulin, and in far lower amounts to alpha1-antitrypsin; small amounts of PSA in the circulation are not bound—i.e., free—to a carrier protein. Prostate cancer is present in 22% of those with PSA levels above 4.0 µg/L, and 60% of those with levels above 10 µg/L.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

PSA

Prostate-specific antigen Urology A 34 kD glycoprotein serine protease with significant homology with other neutral proteases; PSA is secreted exclusively by the prostate epithelium and is responsible for lysing the seminal coagulum; it is present in the serum and is ↑ in Pts with both benign–acute inflammation and BPH and malignant–CA prostate lesions; most serum PSA is bound to protease inhibitors, including α1-antichymotrypin–the form usually measured in the lab, α1-macroglobulin, and in far lower amounts to α1-antitrypsin; small amounts of PSA in the circulation are not bound–ie, free—to a carrier protein; prostate CA is present in 22% of those with PSA levels above 4.0 µg/L, 60% of those with levels above 10 µg/L
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

PSA

Abbreviation for prostate-specific antigen.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

PSA

See PROSTATE-SPECIFIC ANTIGEN.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

PSA (Prostate specific antigen)

A tumor marker associated with prostate cancer.
Mentioned in: Tumor Markers
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

Patient discussion about PSA

Q. Would kidney stones affect a PSA reading? Would drinking lots of grapefruit juice affect a PSA reading? My husband's PSA reading jumped from a 4.2 to a 17 in @ 2 years' time. How can that be? This man takes all sorts of supplements and really watches his diet. He also takes good care of his body, and does NOT look or act 68.

A. You should get your parathyroid gland checked out. Your calcium level might be causing the kidney stones.

Q. Rising PSA to 10 with two negative biospies? Expect cancer? 67 yrs old in good health otherwise.

A. High values don't always mean it's cancer. At 67 years old, you're prostate is most likely enlarging, resulting in the higher PSA results. And after two negative biopsies, it sounds like you're in the clear. Like Brandon said though, keep up with your regular check ups.
Source: http://www.northshore.org/healthresources/encyclopedia/encyclopedia.aspx?Version=Q3_08&DocumentHwid=hw5522&ViewHwid=hw5548

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