Also found in: Wikipedia.


A compound derived from a steroid in which there has been a ring cleavage.
[L. seco, to cut, + steroid]
References in periodicals archive ?
Vitamin D is a secosteroid hormone that plays a vital role in bone metabolism and mineral homeostasis (4).
2]D is a secosteroid hormone that initiates biological actions by interacting with its nuclear receptor at target tissues (Bikle 2014; Carlberg 2014; Haussler et al.
Vitamin D is a secosteroid which has an important function in bone metabolism and immunomodulation.
Vitamin D, which can be generated following ultraviolet light irradiation of the skin, is a secosteroid hormone involved in bone and calcium metabolism.
Vitamin D or cholecalciferol is a pleiotropic secosteroid formed in the body mainly from the action of Ultraviolet B rays on 7-dehydrocholesterol in the skin.
The most intriguing findings were the importance of secosteroid derivatives having oxygenated side chains, although 1 ,-hydroxylation is essential to elicit their biological activity.
Vitamin D is a fat-soluble secosteroid hormone that traditionally has been recognized as a vitamin.
Reversing deficiency and maintaining optimal serum vitamin D levels beneficially impacts biochemistry and numerous body systems; this is largely because calcitriol—the metabolic product of vitamin D—is a secosteroid hormone that targets over 200 genes in a wide variety of tissues.
The principal mechanism for synthesis of the storage form of vitamin D, a potent fat-soluble secosteroid hormone, is skin exposure to sunlight, a mechanism that is less efficient with increasing age.
Avian muscle cells as targets for the secosteroid hormone 1,25-dihydroxy-vitamin D3.
Plotnikoff states that vitamin D is a potent secosteroid hormone with receptors found in every body tissue and a regulator of at least 600 crucial genes.
Actually, D is not a vitamin but a hormone--strictly speaking, a secosteroid, Dr.