Second Pain

One of the two components of acute pain over skin; it is duller and more throbbing than 'first pain,' occurs later, is more unpleasant, indefinite in quality/location and C-fibre mediated

pathophysiological pain

; second pain; slow pain pain that encourages healing by inducing protective behaviours; it originates from stimulation of high-threshold polymodal nociceptors (free nerve endings, present in all tissues and responsive to mechanical, chemical and thermal stimuli) and is transmitted along slow-conduction C fibres (which also induce emotional and behavioural responses to pain via thalamic connections, and activate inhibitory pain pathways and the release of endogenous opioids)
References in periodicals archive ?
BDSI's second pain product, BEMA Buprenorphine, is being developed for the treatment of moderate to severe chronic pain and is in development in a high dose formulation for the treatment of opioid dependence.
A second pain point--that of getting borrowers to respond--is, as the saying goes, only half the battle; the other half being to get the right documents returned in proper shape.
So when they take a life, they really do get away with murder, leaving the families of the victims to carry a second pain, the pain of injustice.
The other drugs are a second pain tablet targeting abusers and an agent used in medical imaging.
She claimed she had caught him with one of her fingernails but as he relaxed again there was a second pain, and he turned his head to see she had a kitchen knife raised above her head ready to stab him again.
The revised protocol was refined further once the program got under way, when it was determined that staff follow-through was still lacking after the second pain assessment.
Smooth Gator's 60 Second Pain Relief(TM) is a cream made from all natural products and regulated by a U.
Jean Taylor, founder of the group, said: "It is very sad that Andy and Christine have had to carry the second pain of injustice for the past six years and that the legal system has let them down.
BDSI's second pain product using the BEMA technology, BEMA Buprenorphine, is in Phase 3 clinical trials for the treatment of moderate to severe chronic pain and is licensed on a worldwide basis to Endo Health Solutions.
BDSI's second pain product using the BEMA technology, BEMA Buprenorphine, is being developed for the treatment of chronic pain and is licensed on a worldwide basis to Endo Health Solutions.
BDSI's second pain product using the BEMA technology, BEMA Buprenorphine, is being developed for the treatment of moderate to severe chronic pain and is licensed on a worldwide basis to Endo Health Solutions.
BDSI's second pain product, BEMA Buprenorphine, just completed Phase 2 clinical development for the treatment of pain and is in development in a higher dose formulation for the treatment of opioid dependence.

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