Veering off the crash course will necessitate many things: foremost, finally and unequivocally recognizing that--whether your preferred analogy is the Apollo Program or the Manhattan Project--energy innovation must be the nation's preeminent scientific priority.
Similarly, Daniel McFadden states that he has a 'strong appreciation for elegant and innovative mathematics and statistics, but as a matter of scientific priority try to keep my research focused on concrete applications'.
Also, the National Institute of Neurological Disorders and Stroke (NINDS) Neuroscience at the New Millennium Plan clearly identifies research on the blood-brain barrier as a scientific priority. The scientific support for this initiative can be found in these reports on the NINDS homepage at http://www.ninds.nih.gov/funding/ neural_environment/index.htm#research
This forced Darwin to go public with The Origin of Species, if he was to ensure its scientific priority. Browne chronicles what life was like for Darwin after that book's publication and during the ensuing debate.