Schilling test


Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia, Wikipedia.
Related to Schilling test: sickling crisis

Schilling test

 [shil´ing]
a test for gastrointestinal absorption of vitamin B12; a measured amount of radioactive vitamin B12 (cyanocobalamin Co 57) is given orally, followed by a parenteral flushing dose of the nonradioactive vitamin, and the percentage of radioactivity is determined in the urine excreted over a 24-hour period. A low urinary excretion that becomes normal after the test is repeated with intrinsic factor is diagnostic of primary pernicious anemia.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

Schil·ling test

(shil'ing),
a procedure for determining the amount of vitamin B12 excreted in the urine using cyanocobalamin tagged with a radioisotope of cobalt.
Farlex Partner Medical Dictionary © Farlex 2012

Schilling test

Vitamin B12 absorption test A test that evaluates ability to absorb vitamin B12, which is ↓ without intrinsic factor, a glycoprotein produced by the gastric parietal cells. See Vitamin B12 deficiency.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Schil·ling test

(shil'ing test)
A procedure for determining the amount of vitamin B12 excreted in the urine, using cyanocobalamin tagged with a radioisotope of cobalt.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Schilling test

A test to demonstrate the failure of absorption of vitamin B12 due to a lack of stomach INTRINSIC FACTOR. The test is used in the investigation of PERNICIOUS ANAEMIA. Cobalt 57 radiolabelled B12 is given by mouth and the amount excreted in the urine over the following 24 hours is an indication of the degree of absorption. (Victor Theodore Schilling, 1883–1960, German haematologist)
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Schilling,

Robert F., U.S. hematologist, 1919–.
Schilling test - a procedure for determining the amount of B12 excreted in the urine. Synonym(s): vitamin B12 absorption test
Medical Eponyms © Farlex 2012
References in periodicals archive ?
Four of 12 patients tested had abnormal results on the Schilling test. Among these 4 patients, 2 had malabsorption.
Her laboratory data, aside from a mild iron deficiency anemia, were within reference values, including a Schilling test, hemoglobin electrophoresis, and homocysteine and MMA concentrations (measured a few weeks after cobalamin injection).
Vitamin [B.sub.12] deficiency: diagnosis and subclassification tests.(a) Frequency Diagnostic Procedure of use utility Cost Blood cell counts (CBC) High Low Low Serum cobalamin High Medium Medium Urine MMA Low High Moderate Serum MMA Low High Moderate Serum homocysteine Medium High Moderate Anti-parietal cell antibody Low Medium Medium Anti-intrinsic factor antibody Low High Medium Serum gastrin Low Moderate Medium Schilling test Low Moderate High Neutrophil lobe count Rare Medium Medium Serum pepsinogen Rare Moderate Moderate Bone marrow examination Low Medium High (a) Tests below the line are rarely used and seldom necessary.