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intracutaneous injection of diluted diphtheria toxin equal to one-fiftieth of the minimum lethal dose. Lack of immunity to diphtheria is indicated by redness and edema appearing at the injection site in 24 to 36 hours and lasting four to five days. This test has now largely been replaced by hemagglutination inhibition tests.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
a test for susceptibility to Corynebacterium diphtheriae toxin: 0.1 mL of Schick test toxin is injected into the skin of one forearm (test site) and the same quantity of the same, but heat-inactivated, material into the skin of the other forearm (control site); those with toxin-neutralizing antibodies either will have no reaction at either injection site (negative test) or may have a pseudoreaction due to antibodies for substances (antigens) in the test materials other than diphtheria toxin; people lacking toxin-neutralizing antibodies may have a positive reaction, which consists of an area of redness appearing 24-36 hours at the test site only and persisting for 4-5 days.
Synonym(s): Schick method
Farlex Partner Medical Dictionary © Farlex 2012
A test to determine immunity to diphtheria by injection into the skin of dilute diphtheria toxin. Inflammation of the injected area indicates a lack of immunity.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Schick testAn obsolete test once used to detect immunity to diphtheria toxin, based on response to subcutaneous heat-inactivated toxin.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Schick test(shik test)
An assessment for susceptibility to Corynebacterium diphtheriae toxin. Schick test toxin is injected into the skin; people lacking toxin-neutralizing antibodies may have a positive reaction, which consists of an area of redness.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
Schick testA skin test of susceptibility to DIPHTHERIA. (Bela Schick, 1877–1967, Hungarian-born American paediatrician).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
Schick,Bela, Austrian pediatrician in U.S., 1877-1967.
Schick method - Synonym(s): Schick test
Schick test - for susceptibility to Corynebacterium diphtheriae toxin. Synonym(s): Schick method
Schick test toxin - Synonym(s): diagnostic diphtheria toxin
Medical Eponyms © Farlex 2012
Schick test(shik test)
An assessment for susceptibility to Corynebacterium diphtheriae toxin.
Medical Dictionary for the Dental Professions © Farlex 2012