Bloom-Richardson grading

(redirected from Scarff-Bloom-Richardson)
Also found in: Acronyms.

Bloom-Richardson grading

A histological system used to stratify breast cancer, in particular ductal carcinoma, into low, intermediate and high grades for the purposes of diagnosis and management.  It is based on three morphologic features:
• Degree of tubule duct formation;
• Mitotic activity;
• Nuclear pleomorphism of tumour cells (nuclear grade).

Bloom-Richardson combined scores
3-5—Well-differentiated (BR low grade)
6-7—Moderately differentiated (BR intermediate grade)
8-9—Poorly differentiated (BR high grade)
References in periodicals archive ?
According to Nottingham modification of Scarff-Bloom-Richardson grading, fifty cases were categorised under three categories.
Prognostic value of histologic grade nuclear components of Scarff-Bloom-Richardson (SBR).
Comparison of the prognostic value of Scarff-Bloom-Richardson and Nottingham histological grades in a series of 825 cases of breast cancer: major importance of the mitotic count as a component of both grading systems.