The nonlyophilized (liquid) form of this therapeutic was administered to dogs with appendicular osteosarcoma following amputation or limb salvage surgery
and chemotherapy consisting of four doses of carboplatin.
By February 2017, Liberty had had six rounds of chemo and a limb salvage surgery
that took over nine hours - but needed a high dose of chemo and a stem-cell transplant in April.
has partnered with Promimic AB, an innovator in nano surface modification, to commercialize Promimic's proprietary Hydroxyapatite (HA) Surface Technologies in Limb Salvage Surgery
Karolinska Development's portfolio company Promimic has formed a new partnership with the U.S company Onkos Surgical to commercialize Promimic's proprietary Hydroxyapatite (HA) Surface Technologies in Limb Salvage Surgery
The patient was treated with salvage surgery
using an intramedullary hindfoot nail and added hybrid external fixation, achieving promising results with regard to this complication.
In most carcinomas other than colorectal tumors, treatment is planned as systemic disease in the presence of recurrence following the resection of the primary lesion and salvage surgery
is not often indicated for the recurrent lesion.
London International Patient Services has previously carried out complex surgery at The London Clinic for several patients including a limb salvage surgery
for an Egyptian military patient who has since returned to work.
He specializes in limb salvage surgery
for peripheral arterial disease and in treating patients for carotid disease, thoracic and abdominal aortic aneurysms, dialysis access and chronic venous disease including deep vein thrombosis.
In three patients a clear surgical margin was not achieved at salvage surgery
. The histology of all APEs performed is summarised in Figure 2.
Successful operative decompression is indicated in early cases to reduce tissue loss and optimize circulation, however, it may be too late for some patients for salvage surgery
and most of those patients may undergo amputation of the necrotic part.
Certainly, further progress in the future with more refined techniques is demanded to establish the justification of this salvage surgery
in the clinic.