SV40


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SV40

SV40

(ĕs′vē-fôr′tē)
n.
A polyomavirus found in humans and other mammals that causes tumors in certain species, such as hamsters and rats, and various diseases in immunocompromised monkeys. It has been widely researched as a model of viral replication and gene expression and a possible cause of certain cancers in humans.
References in periodicals archive ?
(1984) Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen.
The concretes were blended at site, and the fresh concrete temperature for the "low-heat" concrete was about 23.0[degrees]C and for "SV40" about 21.5[degrees]C.
Abbreviations BKPyV: BK polyomavirus JCPyV: JC polyomavirus PVAN: Polyomavirus-associated nephropathy PML: Progressive multifocal leukoencephalopathy PML-IRIS: Progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome VLP: Virus-like particle SV40: Simian virus 40 LT: Large T antigen PBS: Phosphate-buffered saline CCK-8: Cell Counting Kit 8 HAU: Hemagglutination unit.
This region was part of the 3' untranslated region (UTR) and was replaced with a KpnI restriction site followed by an SV40 polyadenylation signal.
In one of the biggest political blunders in medical history, nearly half the American population was given a polio vaccine over the years from 1955 to 1961 that had been contaminated by the cancer-causing SV40 monkey virus.
FitzGerald for assistance with the bioinformatics analysis, and Patti Fetsch for immunocytochemical staining of SV40.
Population-based study of antibody to the human polyomaviruses BKV and JC VIRUS and the simian polyomavirus SV40; Journal of Medica Virology; 2003;71(1):115-123.
Vector GV314 was cotransfected because it contains the marker gene GFP, SV40, CMV promoter, and ampicillin resistance gene.
"BKPyV, JCPyV, and the closely related Simian virus 40 (SV40) were originally grouped with papillomaviruses in the genus Papovavirus, which was later separated into the genera Papillomavirus and Polyomavirus" (Bennett, Broekema, & Imperiale, 2012, p.
PTracer-SV40 is a CHO expression vector that uses SV40 promotor and encodes Green Fluorescence Protein (G FP).
AND KAWAKITA, M., 1963.The research for the SV40 by means of tissue culture technique.
Soon thereafter, another group showed that a different kind of DNA virus, the polyomavirus SV40, also contained an miRNA (3).