SUMO2

SUMO2

A gene on chromosome 17q25.1 that encodes a broadly expressed ubiquitin-like protein, which can be covalently attached to proteins as a monomer or a lysine-linked polymer. This post-translational modification on lysine residues of protein (sumolyation) plays a crucial role in a number of cellular processes, including nuclear transport, DNA replication and repair, mitosis and signal transduction. SUMO2 interacts with PELP1, SAE2 and USP25; it is activated when its precursor form is cleaved by SENP1 or SENP2.
References in periodicals archive ?
The design of a multiple drug combination for treating stage 1 bladder cancer depends on a strategy of inhibiting the highly expressed genes ADRM1, COPS5, PSMD8, SUMO2, CALR, PDIA3, DNAJB11, HSPA5, RPN1, CUL1, HSP90B1, KPNA2, PSMD12, ECT2, TK1, TUBA1C, HN1, and ENO1; activating the suppressed genes UBC, JUN, RARRES3, and FOS; and suppressing the drug's effect on the nondifferentially expressed genes BAG6, HUWE1, PAAF1, PSMD10, FAF2, PCYT1A, and PSMD10.
The design of a multiple drug combination for treating stage 4 bladder cancer depends on a strategy of inhibiting the highly expressed genes ADRM1, COPS5, PSMD8, SUMO2, RNF126, CALR, PDIA3, DNAJB11, HSPA5, RPN1, HSP90AA1, HSPA1B, METTL23, RARRES3, KPNA2, PSMD12, ECT2, JUN, TK1, TUBA1C, HN1, and ENO1; activating the suppressed genes BCL3, FOS, UBC, and GTF2A1; and suppressing the drug's effect on the nondifferentially expressed genes, which are the same as those in stage 1 bladder cancer.
This is the first day that Nike Golf's new SQ SUMO 5000 and SQ SUMO2 5900 drivers are available in stores.
With the SQ SUMO2 5900, we have ensured that square is here to stay.