SULT1A1


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SULT1A1

A gene on chromosome 16p12.1 that encodes an enzyme which sulfonates catecholamines, neurotransmitters, phenolic drugs and minoxidil.
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Whereas the normal SULT1A1 is reactive with Ellman's reagent, the C[70, 168, 287]S mutant is non-reactive as expected.
Beggs et al., "Functional genetic variants in the 3/-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity," Toxicological Sciences, vol.
Analysis of the substrate specificity of human sulfotransferases SULT1A1 and SULT1A3: site-directed mutagenesis and kinetic studies.
Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism.
TBBPA and TCBPA (tetrachlorobisphenol A) have been shown by in vitro studies to be modestly sulfated by SULT1A1 and SULT1E1 (Kester et al.
OH-PCBs are substrates for human SULT1A1. The sulfation of 2'OH-PCB 3, 3'OH-PCB 3, 4'OH-PCB 3, 4'OH-PCB 11, and 4'OH-PCB 12 is catalyzed by a cytosolic extract of E.
To verify those measurements, SULT1A1 and 3'-phosphoadenosine-5'-phosphate (PAP, required for 7-HC binding) were equilibrated by microdialysis at varied [7-HC] and pH.
Dihydroxycoumarin Probes the Active Site of SULT1A1. Sundari Chodavarapu* and Joe D.