SUCNR1

SUCNR1

A gene on chromosome 3q25.1 that encodes a G protein-coupled receptor for succinate, an intermediate metabolite in the citric acid cycle that promotes haematopoietic progenitor cell development.

Molecular pathology
SUCNR1 may play a role in renovascular hypertension which correlates with renal failure, diabetes and atherosclerosis.
References in periodicals archive ?
All five biomarkers are genetic variants of the gene SUCNR1, which is located in a chromosomal region of the human genome identified as 3q24-q27.
SUCNR1 is a receptor gene that acts on succinate in the kidneys to mediate the rennin-angiotensin system (RAS), a hormone system that helps control the body's blood pressure and fluid balance.