STK19

STK19

A gene on chromosome 6p21.33 that encodes a putative serine/threonine kinase of unknown function. It interacts with BAG1.
References in periodicals archive ?
(444,499) Both studies found a recurrent mutation with a UV signature in RAC1 (among other novel driver mutations showing UV signatures in PPP6C and STK19).
On the other hand, repressed genes in malignant tumors correspond to: STK19, a Ser/Thr nuclear protein kinase; ABT1, a transcription co-activator; and CTBP2, a transcriptional repressor which acts as a tumor suppressor and plays an important role in oncogenesis (Chinnadurai, 2002).
The RP1 gene [synonym for the serine/threonine kinase 19 (STK19) gene] encodes a nuclear serine/threonine nuclear kinase; C4 encodes the immune effector protein complement component with isotypes encoded by C4A [complement component 4A (Rodgers blood group)] and C4B [complement component 4B (Chido blood group)]; and TNX encodes a member of the extracellular matrix protein family.