AURKB

(redirected from STK1)

AURKB

A gene on chromosome 17p13.1 that encodes Aurora kinase B, which is involved in regulating many mitotic events. Aurora B is the catalytic component of the chromosomal passenger complex (CPC), which is critical for the correct progression through and completion of mitosis. It phosphorylates the CPC subunits BIRC5/survivin, CDCA8/borealin and INCENP, the last of which increases AURKB activity.
References in periodicals archive ?
The cause of PJS is a mutant gene named STK1, also known as LKB1.
Cell culture of human gingival fibroblasts, oral cancer cells and mesothelioma cells with serum-free media, STK1 and STK2.
FLT3 (Fms-like tyrosine kinase-3), also known as FLK2 (fetal liver kinase-2) and STK1 (human stem cell kinase-1), was originally isolated as a hematopoietic progenitor cell-specific kinase and belongs to Class-III receptor tyrosine kinase (RTK) family to which c-Fms, c-Kit, and the PDGFR (platelet derived growth factor receptor) also belong [1].
The fms-like tyrosine kinase 3 (FLT3), also known as stem cell tyrosine kinase-1 (STK1) or fetal liver tyrosine kinase-2 (FLK-2), belongs to the group of class III receptor tyrosine kinases (RTKs), which also include the receptors c-kit and c-fms.
(1,2) FMS-like tyrosine kinase 3 (FLT3), also known as stem cell tyrosine kinase 1 (STK1) or fetal liver kinase 2 (flk2), belongs to the group of class 3 receptor tyrosine kinases.