(2008) found that the expression level of PRLR tended to be opposite to that of
STAT5a in common breast epithelial cells.
Progesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and
stat5a. Oncogene 2015;34:3676-87.
Stephens, "
STAT5A Expression in Swiss 3T3 Cells Promotes Adipogenesis In Vivo in an Athymic Mice Model System," Obesity, vol.
Hendricks et al., "Progesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and
Stat5a," Oncogene, vol.
The expression of PPAR[gamma] (Figure 4(d)),
STAT5A (Figure 4(e)), and SREBP 1c (Figure 4(f)) was established.
In NAFLD&NASH, we observed that oxidative stress could activate epidermal growth factor receptor (EGFR) to facilitate (i) UBC to repress HSF1 in the WNT and MAPK signaling pathways; (ii) APP to activate ETS1 in the MAPK signaling pathway to induce DNA repair function through the mediation of RFC5, to activate metabolism through the mediation of TRMT1, and to inhibit apoptosis through the mediation of ZNF480; and (iii) SHC1 to repress
STAT5A in the MAPK signaling pathway.
[5.] Nakajima H, Liu XW, Wynshaw-Boris A, et al An indirect effect of
Stat5a in IL-2- induced proliferation: a critical role for
Stat5a in IL-2- mediated IL-2 receptor alpha chain induction.
The carcinoma was positive for cytokeratin (CK) 7 (Figure 1, G), CK18, mammaglobin (Figure 1, H), S100 protein (S100) (Figure 1, I), and signal transducer and activator of transcription 5a (
STAT5a); focally positive for p63 protein (p63); and negative for gross cystic disease fluid protein 15 (GCDFP-15), discovered on GIST-1 (DOG1), smooth muscle actin (SMA), calponin, and estrogen receptor/ progesterone receptor (ER/PR).
Determination of the novel genetic variants of goat
STAT5A gene and their effects on body measurement traits in two Chinese native breeds.
Four types of JAK (JAK1, JAK2, JAK3, and Tyk2) and seven types of STAT (STAT1, STAT2, STAT3, STAT4,
STAT5a, STAT5b, and STAT6) proteins exist.
Hennighausen, "
Stat5a is mandatory for adult mammary gland development and lactogenesis," Genes & Development, vol.
In mammals, the STAT family is comprised of seven members (STAT1, STAT2, STAT3, STAT4,
STAT5a, STAT5b, and STAT6) and there are four tyrosine kinases identified (JAK1, JAK2, JAK3, and TYK2) [10].