SSTR2

SSTR2

A gene on chromosome 17q24 that encodes a G protein-coupled somatostatin receptor for somatostatin-14 and -28. It interacts with SHANK1 and is expressed in the brain and kidneys.
References in periodicals archive ?
Signifor LAR has the potential to stimulate both SSTR2 and SSTR5 subtype receptors, which are relevant for inhibition of GH and IGF-1 secretion, making Signifor LAR a more effective treatment for acromegaly compared to other SSAs currently used to treat this disease[sup.
The sensitivity is reduced if there is a lack of SSTR2 expression, as is seen in poorly differentiated NETs and insulinomas.
Our recent experiments have localised SSTR2, SSTR3 and SSTR5 on the surface of the egg and worm stages of the parasite in host liver and ileum using immunohistochemistry, dot blot and western blotting techniques (Fig.
Retrieval of SSTR sequences: The sequences of human, mouse and rat SSTR2, 3 and 5 were retrieved from Swiss-Prot (10-12) using the sequence retrieval system 5 (SRS) (Table 1a-c).
mansoni genome database maintained at the European Bioinformatics Institute (EBI) was searched for the presence of sequence(s) of SSTR2, 3 and 5 using tBLASTn (13,14) using default parameters (Table 2).