SCN5A

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SCN5A

A gene on chromosome 3p21 that encodes an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel alpha subunit, which is expressed primarily in cardiac myocytes and is responsible beginning the action potential as seen on an ECG/EKG.
 
Molecular pathology
SCN5A mutations are long QT syndrome type 3.
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References in periodicals archive ?
In the south region (SSS1 and SSS2), the influence of coastal water, with the La Plata front (Piola et al., 2000) may have contributed to lower temperature observed.
For the transects of the arrangement farther to the south (SSB4; SSS1 and SSS2), there was observed the high densities of diatoms and silicoflagellates, which are related to a higher concentration of silicate in this region, especially during the winter, with the two largest river inputs in the south region (Rio de la Plata and the Lagoa dos Patos Estuary (Piola et al., 2000), in addition to the high concentration of nutrients (Rigual-Hernandez et al., 2010).
The prevalence of Chaetognatha (SSB1, SSB2, SSB4, SSS1), Copepoda (Acartia sp., Temora stylifera, Temora turbinada, Oithona plumifera, Oithona sp., Paracalanus sp.) in SSB1 and Cladocera (Penilia avirostris) (SSB1, SSB2 and SSB3), are indicative of Coastal Water (WC) and its association with estuarine regions (Resgalla Jr.
Highlight of the transects of the southeast and south regions of Brazil (solid line: sSb1, SSB2, SSB3, SSB4, SSS1, SSS2).
With the aid of the SSS1 program, an analysis of temporary series was run using iterative procedures for an ARIMA model construction.
Con ayuda del programa SSS1 (12) se efectuo un analisis de series temporales a fin de observar la tendencia y estacionalidad de los datos, ademas de ajustar un modelo pronostico.