SOCS3

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SOCS3

A gene on chromosome 17q25.3 that encodes a protein which interacts with multiple activated proteins of the tyrosine kinase signalling pathway, including IGF1 receptor, insulin receptor and JAK2.

Molecular pathology
SOCS3 is thought to be a susceptibility gene for atopic dermatitis.
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5)/M_RUCY; PER= (&L)/((&L-2)*(&M-l)); SUF= (&L-1)*(&L-2)*(&M-1); SIGMA= (PER*GE); RS=YS_TINT/SUF; SIGMA=SIGMA-RS; T=ROUNDE (&L/3); L=ROUNDE(2*T); IF RUCY<T THEN FOX='Top'; IF T<=RUCY<L THEN FOX='Mid'; IF L<=RUCY THEN FOX='Low'; PROC MEANS DATA=RANKS MEAN SUM NOPRINT; BY Genotype; VAR SIGMA SI2 SI3 SI6 NP1 NP2 NP3; OUTPUT OUT=NONP MEAN = L_SIGMA SI2 SI3 SSI6 NP1 NP2 NP3 SUM=S_SIGMA SSI2 SSI3 SI6 SNP1 SNP2 SNP3; RUN; %MACRO RANK (D =, VAR=); DATA &D; ARRAY E{&M}; DO J=1 TO &M; SET RANKS; BY Genotype; E{J} = &VAR; END; IF LAST.