MSR1(redirected from SR-A)
Also found in: Acronyms.
MSR1A gene on chromosome 8p22 that encodes the class-A macrophage scavenger receptors, which include three different types (1, 2 and 3) generated by alternative splicing of MSR1. The receptor isoforms have been implicated in both macrophage-associated physiological and pathological processes, including atherosclerosis, Alzheimer's disease and host defence.
Defects in MSR1 have been linked to an increased susceptibility to prostate cancer and Barrett’s oesophagus.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.