SOST


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SOST

A gene on chromosome17q11.2 that encodes sclerostin, a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists.

Molecular pathology
Loss-of-function mutations in SOST are linked to sclerosteosis; a deletion downstream of SOST causes reduced sclerostin expression, resulting in a milder sclerosteosis (van Buchem disease).
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The numeral sostumm in sentence (34) refers to the noun phrase sost awrewocc 'three animals' in the preceding subordinate clause.
Informed sources told that according to rules and regulations every year the employees of Pak-China Sost Dry Port Co.
Sclerostin, the protein product of the osteocyte gene SOST, competitively binds to LRP5 and blocks Wnt functioning.
Oogi, Kala Dhaka and Darband areas of Mansehra district, Shalnai, Jambela, Sost Viyar, Thakot, Goryal Bala, Goryal Payan and Kund areas of Battagram district and Basham area of Shangla district have been put on red alert.
Sclerostin is produced by a gene called SOST, and individuals with mutations in that gene have sclerosteosis, a congenital disease characterized by extremely high bone mass, often leading to increased intracranial pressure and death.
Also, more history can be found in [Olga Bakich, sost.
PTDC's General Manager Motels Sheikh Fayyaz Ahmed told Thursday that the offer was valid for its facilities in Ayubia, Naran, Saidu Sharif, Miandam, Chitral, Bamburet (Kalash Valley), Mastuj, Phandar, Gupis, Gilgit, Hunza, Sost (Pak-China border), Rama Lake, Skardu, Khaplu and Besham resorts.
He said PTDC's tourist resorts in Northern Areas Gilgit-Baltistan were Chinnar Inn, Gilgit, PTDC Motel, Hunza, PTDC Motel, Sost (Pak-China border), K-2 Motel, Skardu,PTDC Motel, Gupis (Distt.
ISLAMABAD, May 16 -- The water level at Attaabad Lake has risen to 341 feet, prompting the local traders to evacuate the area of Sost near the Pak-China border on Saturday.
ISLAMABAD -- Minister for Kashmir Affairs and Gilgit-Baltistan, Chaudhry Muhammad Barjees Tahir Tuesday directed the officials concerned for formulating a comprehensive distribution formula of revenue collection at Sost Border for the development of Gilgit-Baltistan.
He said PTDC's tourist resorts in northern areas Gilgit-Baltistan were including Chinar Inn, Gilgit, PTDC Motel, Hunza, PTDC Motel, Sost (Pak-China border), K-2 Motel, Skardu, PTDC Motel, Gupis (Distt.
The SNPs on chromosome 17 are adjacent to the SOST gene, which encodes sclerostin, a protein involved in the formation of bone.