But bacteria have a repair system, aptly called the SOS response
, to fix DNA breaks.
In this study we demonstrate that curcumin is able to inhibit the SOS response
in Escherichia coli induced by levofloxacin.
The Role of a UvrD Helicase and the SOS Response
in Pseudomonas syringae pv.
The research reveals for the first time the relation between the bacteria DNA repair system, known as SOS response
, and swarming.
The petition was submitted as part of the SOS response
to the draft Appropriate Assessment.
edu/EcoGene/EcoWeb) they focused on were the principal mediators of the SOS response
, recA (recombinase gene A, locator EC10823) and lexA (lambda excision gene A, locator EC10533); genes with known involvement in the SOS response
, ssb (single strand binding gene, locator EC10976), reef (recombinase gene F, locator ECI0828), dinI (damage inducible gene I, locator EC 12670), umuDC (UV mutator gene, locator EC11057); and three sigma factor genes whose function in SOS response
is not clearly identified, rpoD (RNA polymerase factor subunit D, locator EC10896), rpoH (RNA polymerase factor subunit H, locator EC10897), and WoS (RNA polymerasc f~actor subunit S, locator EC10510).
Another effect of the SOS response
, activated by fluoroquinolone-induced damage to the bacterial DNA, is the discontinuation of cell replication.
This research builds on previous findings that beet armyworm caterpillars elicit a chemical SOS response
Ciprofloxacin belongs to the SOS-inducing antibiotics, which induce the so called SOS response
in bacteria, a response that may lead to induction of resistance to the drug.
Conventional antibiotics can trigger the SOS response
in bacteria that actually enhances virulence.
Historically, the expression of bacterial SOS response
genes was used for detecting genotoxicity of chemicals.
Phage production is linked to induction of the bacterial SOS response
, a ubiquitous response to DNA damage.