Although use of chlortetracycline and oxytetracycline in cattle is not consistent (4), the levels of SOS response
induction and Stx phage propagation by these 2 antibiotics were comparable (Figure 1).
Separation of recombination and SOS response
in Escherichia coli RecA suggests LexA interaction sites.
Induction of the SOS response
in ?mreB, ?mreC, and ?mreD cells
Genes that control protein repair, such as hslU, and systems of DNA repair, such as the SOS response
, were engaged.
The RecA filament promotes the LexA cleavage reaction inducing the expression of the SOS response
genes (Kim et al.
Our hypothesis is that the reduced virulence seen in the Pst DC3000 uvrD mutant is due to perturbation of the SOS response
. In order to test this hypothesis, we are generating lexA mutants of Pst DC3000.
Researchers have shown that the presence of antibiotics activates SOS response
and thus increases concentration of RecA protein.
Figure 3 illustrates a literature-based linkage map between genes in the SOS response
for the repair of DNA damage.
A bare look at tasks undertaken, definitely stands a testimony to this fact; terrorism, militancy in Baluchistan, restoration of peace in Karachi, frequent escalations on L of C/working boundary, Indian intrigues on western border in league with Afghan NDS, US mantra of Do More, tight rope diplomacy, international commitments, provision of infrastructure and rehabilitation of IDPs in FATA/other terror hit areas, fencing of Afghan border, security of CPEC, handling issues of riot control, relief work in calamities of different Kinds, enterprises of national importance national census and holding of PLS matches and emergencies calling SOS response
. Last but not the least, holding free, fair and transparent General Elections 2018 under their supervision albeit their plate was full.
Filamentation is part of the SOS response
, which is a set of physiological and biochemical modifications in response to DNA damage induced by chemical and physical agents (11).
"Conventional antibiotics can trigger the SOS response
in bacteria that actually enhances virulence.
Historically, the expression of bacterial SOS response
genes was used for detecting genotoxicity of chemicals.