SON


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SON

A gene on chromosome 21q22.11 that encodes an RNA-binding protein which acts as a mRNA splicing cofactor by promoting efficient splicing of cell cycle and DNA-repair transcripts (e.g., TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A and FANCG), which possess weak splice sites. SON also binds to DNA and may indirectly repress hepatitis-B virus (HBV) core promoter activity, as well as transcription of HBV genes and production of HBV virions.
References in classic literature ?
28-30) And....on's son sought her to wife (and brought)
34-41) And from Phylace two men of exceeding worth sought her to wife, Podarces son of Iphiclus, Phylacus' son, and Actor's noble son, overbearing Protesilaus.
43-49) From Athens the son of Peteous, Menestheus, sought her to wife, and offered many bridal-gifts; for he possessed very many stored treasures, gold and cauldrons and tripods, fine things which lay hid in the house of the lord Peteous, and with them his heart urged him to win his bride by giving more gifts than any other; for he thought that no one of all the heroes would surpass him in possessions and gifts.
50-51) There came also by ship from Crete to the house of the son of Oebalus strong Lycomedes for rich-haired Helen's sake.
"Dread son of Saturn," answered Juno, "what are you talking about?
Juno smiled at this, and as she smiled she took the cup from her son's hands.
You forget this, and threaten to rob me of the prize for which I have toiled, and which the sons of the Achaeans have given me.
Surely Priam with his sons would rejoice, and the Trojans be glad at heart if they could hear this quarrel between you two, who are so excellent in fight and counsel.
He thought he was going to avenge the murder of his son, whereas in truth he was never to return, but was himself to perish in his attempt.
Then Minerva said to Jove, "Father, son of Saturn, king of kings, answer me this question--What do you propose to do?
Ulysses was glad when he saw her, and said to his son Telemachus, "Telemachus, now that you are about to fight in an engagement, which will show every man's mettle, be sure not to disgrace your ancestors, who were eminent for their strength and courage all the world over."
My son and grandson are vying with one another in the matter of valour."