SOCS6(redirected from SOCS-6)
SOCS6A gene on chromosome 18q21.2 that encodes a protein belonging to the cytokine-induced STAT inhibitor (CIS)—i.e., suppressor of cytokine signalling (SOCS); STAT-induced STAT inhibitor (SSI)—protein family, which are cytokine-inducible (e.g., by CSF2/GM-CSF, erythropoeitin) negative regulators of cytokine signalling.
SOCS6 is highly expressed in chronic myeloid leukaemia (CML) and erythroleukaemia.
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