SOCS5

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SOCS5

A gene on chromosome 2p21 that encodes a protein of the suppressor of cytokine-signalling (SOCS)—i.e., STAT-induced STAT inhibitor (SSI)—protein family, which are cytokine-inducible negative regulators of cytokine signalling. SOCS5’s specific function is unknown.
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References in periodicals archive ?
There are seven SOCS family proteins: SOCS-1, SOCS-2, SOCS-3, SOCS-4, SOCS-5, SOCS-6, and SOCS-7, each of which has a central SH2 domain, an amino-terminal domain of variable length and sequence, and a carboxy-terminal 40-amino-acid module known as the SOCS box (Tamiya et al.