SNRNP40

SNRNP40

A gene on chromosome 1p35.2 that encodes a member of the WD-repeat protein family belonging the U5 small nuclear ribonucleoprotein (snRNP) complex. The U5 snRNP is part of the spliceosome, a multiprotein complex that removes introns from pre-messenger RNAs.
References in periodicals archive ?
Functional enrichment analysis for two upregulated modules (up-1 and up-2) with a higher enrichment score showed that the genes in module up-1 (e.g., DHX9, HNRNPA2B1, HNRNPR, GTF2F2, and SNRNP40) were mainly enriched in RNA splicing (P=1.53E-17) and mRNA processing (P=3.94E-14) pathways.
DEGs in module up-1, such as POLR2G, POLR2F, DDX23, PRIM1, MCM3, TK1, SNRNP40, SNRNP70, and RNASEH2A, were significantly enriched in three pathways of pyrimidine metabolism (P=1.15E-03), DNA replication (P=5.24E-03), and spliceosome (P=4.41E-02).