Smith-Lemli-Opitz syndrome

(redirected from SLOS)
Also found in: Acronyms.

Smith-Lemli-Opitz syndrome

 [smith´lem´le o´pitz]
a hereditary syndrome, transmitted as an autosomal recessive trait, characterized by microcephaly, mental retardation, hypotonia, incomplete development of male genitalia, short nose with anteverted nostrils, and syndactyly of the second and third toes.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

Smith-Lem·li-O·pitz syn·drome

(smith lem'lē ō'pits), [MIM*270400]
mental retardation, small stature, anteverted nostrils, ptosis, male genital anomalies, and syndactyly of the second and third toes, often in breech-born babies with delayed fetal activity; inherited as an autosomal recessive trait.

Smith-Lem·li-O·pitz syn·drome

(smith lem'lē ō'pits), [MIM*270400]
mental retardation, small stature, anteverted nostrils, ptosis, male genital anomalies, and syndactyly of the second and third toes, often in breech-born babies with delayed fetal activity; inherited as an autosomal recessive trait.
Farlex Partner Medical Dictionary © Farlex 2012

Smith-Lemli-Opitz syndrome

Neonatology A rare AR condition characterized by multiorgan birth defects, with microcephaly, hypotonia, dysmorphic facies–short nose with anteverted nares, ptosis of eyelids, micrognathia, poly- and/or syndactyly, ♂ genital disorders–cryptorchidism, hypospadias, endocrine defects, cataracts, cardiac and renal malformations, major mental retardation, FTT, high infant mortality Lab ↓ Cholesterol in < 5th percentile, ↑–2000 x normal cholesterol precursor 7-dehydrocholesterol–detected by GC which may be incorporated into cell membranes, interfering with proper functioning
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Lemli,

Luc, 20th century U.S. pediatrician.
Smith-Lemli-Opitz syndrome - see under Smith, David W

Opitz,

John Marius, U.S. pediatrician, 1935–.
Opitz-Frias syndrome - males affected from birth; swallowing problems with recurrent aspiration, stridorous breathing, and hoarse cry.
Opitz-Kaveggia syndrome - in males; X-linked recessive syndrome of multiple congenital anomalies and mental retardation.
Smith-Lemli-Opitz syndrome - see under Smith, David W

Smith,

David W., U.S. pediatrician, 1926-1981.
Marshall-Smith syndrome - Synonym(s): Marshall syndrome
Mulvihill-Smith syndrome - see under Mulvihill-J
Smith-Lemli-Opitz syndrome - mental retardation, small stature, anteverted nostrils, ptosis, male genital anomalies, and syndactyly of the second and third toes.
Medical Eponyms © Farlex 2012
References in periodicals archive ?
Smith-Lemli-Opitz syndrome (SLOS) [5] is a serious disorder associated with dysmorphology and mental retardation.
Exemplary on SLO elaboration and alignment with assessment measure (B.2 & B.3).
Comparison was made between textbook content and the SLOs as mentioned in National Curriculum of 2006 for Mathematics I-XII.
School Liaison Officers (SLOs) also network, educate, and work in partnership with local schools to provide caring adults to enhance the education experience.
The patient materials from the SLOS, CTX, and sitosterolemia patients were obtained before treatment and therefore represent diagnostic samples.
She said banks surveyed still keep the same credit standards for enterprises and households loans for the 41 straight quarters or since the SLOS started in the second quarter of 2009.
Attempting to specify intermediate SLOs without a thorough understanding of the distal outcome (informed by theory and research) is likely to result in SLOs that are misguided.
"Crucially, students are provided time to reflect on information delivered, ask questions and discuss examples of legislation in practice with peers and the SLO.
Second, we derive closed-form expressions for the downlink transmit power required for some desired per-user data rate under each scenario, and we show that the higher data rate achieved with SLOs configuration is at the price of higher power consumption compared to the use of CLO.
To better define these broad terms, WCU used the literature (a sample of which is provided below) to develop a set of five student learning outcomes (SLOs) for each skill.
As Predictive Analytics become more mainstream, SLAs and SLOs are rising and businesses' service level expectations are even higher.
In its quarterly Senior Bank Loan Officers' Survey (SLOS), the Central Bank said respondent banks continued to indicate a net tightening of overall credit standards for commercial real-estate loans for the 11th consecutive quarter based on the diffusion index (DI) approach.