SLCO2B1

SLCO2B1

A gene on chromosome 11q13 that encodes a transporter which mediates Na+-independent uptake of organic anions—e.g., taurocholate; the prostaglandins PGD2, PGE1 and PGE2; leukotriene C4; thromboxane B2; and iloprost.
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References in periodicals archive ?
Ostrander et al., "Expression of SLCO transport genes in castration-resistant prostate cancer and impact of genetic variation in SLCO1B3 and SLCO2B1 on prostate cancer outcomes," Cancer Epidemiology Biomarkers and Prevention, vol.
Mostaghel et al., "SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer," Journal of Clinical Oncology, vol.
variants CYP450 CYP1A2 6 CYP2A6 7 CYP2B6 10 CYP2C19 12 CYP2C8 4 CYP2C9 10 CYP2D6 18 CYP2E1 1 CYP2J2 5 CYP3A4 2 CYP3A5 8 Non-CYP enzymes CDA 2 DPYD 6 FMO2 1 FMO3 2 GSTP1 2 NAT1 12 NAT2 7 TPMT 5 UGT1A1 9 Transporters ABCB1 6 ABCC2 6 SLCO1B1 9 SLCO2B1 1 SLC15A2 4 SLC22A1 6 SLC22A2 4 (a) Variants tested include SNPs, insertions, deletions, triallelic variants, and nucleotide repeats.