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The researchers performed a three-stage genome-wide association study (GWAS) of 13,123 participants to identify genetic variants associated with differences in metformin response, and found a common variant of the gene SLC2A2 that was correlated with a strong response to the drug.
sup][17] observed the amplification of genes BCHE and SLC2A2 at 3q26 in squamous cell lung carcinomas, whereas no amplification has been found in genes MME and KNG .
33E-04 ADRA2B,APOA2,CETP,CNR1, 24 CYP46A1,DCX,DDC,ESR1,GNR HR,GRIA3,GRIN1,IGHM,LPL, MRC1,MTNR1A,PARP15,PDE3A, RAB6A,REG1A,SCN10A, SCN11A,SCN2B,SERPINA1, SLC2A2 Tobacco-related 1.
092 (facilitated glucose (GLUT1) transporter), member 1 solute carrier family 2 SLC2A2 5.