SLC1A4

SLC1A4

A gene on chromosome 2p15-p13 that encodes solute carrier family 1 member 4, a sodium-dependent transporter for glutamate and neutral amino acids—alanine, serine, cysteine and threonine.
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References in periodicals archive ?
has shown that androgens promote glutamine uptake in AR-positive prostate cancer cell lines by inducing expression of two glutamine transporters, SLC1A4 and SLC1A5 [116].
Of these, Slc1a4 and Glx are downregulated in aging fibroblasts, whereas the other 4 are upregulated, and, therefore, would not explain the increase in extracellular redox potential.
The two pathways most strongly associated with alcohol dependence when using 10kb flanking regions were the 'Na+/Cl- dependent neurotransmitter transporters' pathway (#15) (SLC6A1, SLC6A2, SLC6A3, SLC6A5, SLC6A6, SLC6A7, SLC6A9, SLC6A11, SLC6A12, SLC6A13, SLC6A14, SLC6A15, SLC6A18, SLC6A19, SLC6A20, SLC18A1, SLC18A2, and SLC22A2) and the 'amino acid transport across the plasma membrane' pathway (#18) (SLC1A4, SLC1A5, SLC3A1, SLC3A2, SLC6A6, SLC6A12, SLC6A14, SLC6A15, SLC6A18, SLC6A19, SLC6A20, SLC7A1, SLC7A2, SLC7A3, SLC7A5, SLC7A6, SLC7A7, SLC7A8, SLC7A9, SLC7A10, SLC7A11, SLC16A10, SLC36A1, SLC36A2, SLC38A1, SLC38A2, SLC38A3, SLC38A4, SLC38A5, SLC43A1, and SLC43A2) (both p = 1.8E-3).