MBTPS1

(redirected from SKI1)

MBTPS1

A gene on chromosome 16q24 that encodes a sterol-regulated subtilisin-like serine protease, which cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), releasing transcriptionally active SREBP fragments for translocation to the nucleus.
References in periodicals archive ?
Similarly, the CLV_PCSK_SKI1_1 motif matched with amino acid residues RDLKV (323-327), a functional motif of Subtilisin/kexin isozyme-1 (SKI1) cleavage site ([RK]-X-[hydrophobic]-[LTKF]-|-X) of endoplasmic reticulum lumen and Golgi apparatus.
Incheon Saccostrea Gangjeong-dong, 2 SKI1 (l) KP067909 kegaki Seogwipo-si, Jeju-do SKE2 (1) KP067910 TABLE 2.