SIX6

SIX6

A gene on chromosome 14q23.1 that encodes a member of the sine oculis homeobox (SIX) transcription factor family which plays a role in eye development.

Molecular pathology
SIX6 mutations may cause microphthalmia with cataract type 2 (MCOPCT2).
References in periodicals archive ?
In a 2010 group show, "Six6," that Weldon was part of, its curator Isa Lorenzo writes, "(Weldon's) personal work has always been about finding the spaces in between life's daily grind, and harvesting the good out of them." In 2014, she released a series focusing on drops of water, highlighting order, symmetry, and the play of light.
Moreover, the number of farmers in Egypt is nearly six6 million, and there is a temporary agricultural labour estimated to be four million.
Tenders are invited for Making six6 nos ventilation stoppings and replastering of twelve 12 nos old ventilation stoppings from 5th wl to 16th wl in bansgarha seam of bhurkunda b colliery barka sayal area
These genes encoded proteins primarily involved in integrin signalling pathways (ACTA2, PIK3C2G, COL4A6, CAV1, LAMA1, FN1, and ITGA8), regulation of hormone levels (NR5A1, TIPARP, ACE, CRYM, CGA, ALDH1A1, TBX3, POMC, GHRH, and ALDH6), camera-type eye development (TGFBR2, BMP4, FABP7, STRA6, SIX6, and WNT6), blood vessel development (Figure S1, goo.gl/tC9GTZ), and regulation of cellular response to growth factor stimulus (see Figure 2).
The reverse transcriptionPCR also demonstrated that differentiated cells expressed EF transcription factors (EFTFs), PAX6, LHX2, RX, SIX3, and SIX6 on D14 with negative or low expression of pluripotency marker OCT4 (Figure 2(i)).
Within the neural epithelial-derived optic vesicle, animal studies have demonstrated that Pax6 acts together with additional transcription factors such as Pax2, Six6, Gsx2, Pax5, and Lhx2 to regulate invagination to form the bilayered cup that will become the retina, retinal pigmented epithelium, and iris pigmented epithelium [8, 10, 12, 46].
A novel genetic variant of the goat Six6 gene and its association with production traits in Chinese goat breeds.
Forty-five genes implicated in the CC, including 29 nonsyndromic cataract genes ( AGK , BEST1 , BFSP1 , BFSP2 , CHMP4B , CRYAA , CRYAB , CRYBA1 , CRYBA4 , CRYBB1 , CRYBB2 , CRYBB3 , CRYGC , CRYGD , CRYGS , EPHA2 , FYCO1 , GJA3 , GJA8 , HSF4 , P3H2 , LIM2 , MAF , MIP , NHS , PITX3 , SLC16A12 , TDRD7 , and VIM ) and 16 syndromic cataract genes ( ABHD12 , CNBP , CTDP1 , EYA1 , FTL , GALK1 , GCNT2 , GFER , GJA1 , JAM3 , OPA3 , PAX6 , RAB3GAP2 , SIL1 , SIX6 , and SLC33A1 ), were collected from careful literature and database search.
Dharamsala: The battle for pride between the ousted teams, the Netherlands and Ireland, turned out to be a slam-bang affair after rain reduced the game into a 'Six6' affair in the Group A competition of the ICC World T20 match at the HPCA Stadium here on Sunday.
They found that the expression of a variant of SIX6 and elevated intraocular pressure promote glaucoma by boosting p16INK4a, leading to the eventual demise of retinal ganglion cells.
Police and Rangers conducted a raid at thehouse and seized two SMGs rifles Kalashnikovs 19 30-bore pistols six6
For this purpose 18 rabbits of almost same body weight and age were randomly divided into three groups (six6 animals per group) designated as A, B and C.