SIX3

SIX3

A gene on chromosome 2p21 that encodes a member of the sine oculis homeobox (SIX) transcription factor family which plays a role in eye development.

Molecular pathology
SIX3 mutations are associated with holoprosencephaly type 2.
References in periodicals archive ?
Four genes for holoprosencephaly are known: SHH (7q36), ZIC2 (13q32), SIX3 (2p21), and TGIF mapped in the distal most part of the short arm of chromosome 18 (18p11.
Asimismo, se han encontrado mutaciones en 9 genes como causantes de HPE: SHH, PTCH, GLI2, DHCR7, ZIC2, TDGF1, TGIF, FAST1 y SIX3.
GTCR REPORTEDLY PICKS GOLDMAN, JPMORGAN TO RUN SALE OF SIX3 SYSTEMS
GTCR'S SIX3 SYSTEMS BUYS MISSION-CRITICAL SOLUTIONS FIRM TICOM GEOMATICS
US SIX3 SYSTEMS TAKES OVER INTELLIGENCE SOFTWARE FIRM NOVII DESIGN