SIX1

A gene on chromosome 14q23.1 that encodes a homeobox protein similar to the Drosophila “sine oculis” gene product and thought to be involved in limb development.

Molecular pathology
SIX1 mutations are linked to autosomal dominant deafness type 23 and branchiootic syndrome type 3.

References in periodicals archive ?

The transcriptional coactivator Eya1 and the homeobox gene Six1 are believed to participate in the early differentiation of hair cells and neurons (10), which are in turn regulated by Foxil (11).

Genetic Causes of Inner Ear Anomalies: a Review from the Turkish Study Group for Inner Ear Anomalies

Expression and significance of Six1 and Ezrin in cervical cancer tissue.

Overexpression of ezrin and galectin-3 as predictors of poor prognosis of cervical cancer

Similar observations were seen in overexpression of MyoD in P19 embryonal carcinoma stem cells, which can induce paraxial mesodermal genes including Meox1, Pax3, Pax7, Six1, and Eya2 followed by muscle-specific genes.

Skeletal Muscle Cell Induction from Pluripotent Stem Cells

PAX3 and SIX1 expression by immunohistochemistry (43) and gene-expression analysis (44) has recently been identified in borderline and malignant PTs and correlates with a poor clinical outcome.

Phyllodes Tumor of the Breast: Histopathologic Features, Differential Diagnosis, and Molecular/Genetic Updates

P53 expression level is decreased by Sineoculishomeobox homolog 1 (Six1) in response to DNA damage in a proteasome independent manner [15].

The role of Six1 signaling in paclitaxel-dependent apoptosis in MCF-7 cell line

Since the loss of E-cadherin expression is considered a crucial event in EMT, EMT-TFs have been classified based on their ability to repress E-cadherin directly (SNAIL, SLUG, ZEB1, ZEB2, etc.) or indirectly (TWIST1, TWIST2, E2.2 SIX1, FOXC2, etc.) [46].

Sirtuins and Cancer: Role in the Epithelial-Mesenchymal Transition

There was the further "discovery" of single digits 6 and 7 on six1 folios (including the number 6 on V&A 1508-1883 I.S.), which were proposed as "volume numbers" (Seyller 1993, p.

Dating the Hamzanama: a re-examination

Gene expression responses over 24 h to lengthening and shortening contractions in human muscle: major changes in CSRP3, MUSTN1, SIX1, and FBXO32.

RESPOSTAS NEUROMORFOLOGICAS REFERENTES A UM PROTOCOLO DE TREINO RESISTIDO COM ENFASE NA ACAO MUSCULAR ISOMETRICA

Tokyo, Nov 20, 2014 - (JCN Newswire) - Toyota Motor Corporation will hold a series of six1 classical-music concerts in cities throughout Japan between April 2 and April 12, 2015.

Toyota Aims to Inspire Current and Future Music Lovers with 2015 Concert Series in Japan

Early in human development, we depend on a transcription factor called SIX1 to create this weed-like growth and nimble movement.

How tumours flip 'on-off' signals to promote or suppress breast cancer

Estos genes incluyen factores de transcripcion como Six1. que se expresa inicialmente en toda el area preplacodal: Pax8, expresado en el dominio posterior del sector preplacodal, los cuales son precursores de la placoda otica.

Desarrollo embrionario del sistema nervioso central y organos de los sentidos: revision