SHH


Also found in: Dictionary, Financial, Acronyms, Encyclopedia, Wikipedia.

SHH

A gene on chromosome 7q36 that encodes a protein central in early embryonic patterning and the key inductive signal in patterning of the anterior-posterior limb axis, the ventral somites and the ventral neural tube.

Molecular pathology
Defects in SHH or in its signalling pathway cause holoprosencephaly, VACTERL syndrome; mutation upstream of SHH disrupts limb patterning and can result in preaxial polydactyly.
References in periodicals archive ?
Flecha blanca indica capa interna del iris inmunopositiva y fecha roja indica capa externa del iris negativa a Shh. C.
Caption: Figure 1: (a) Subject-matched ntMSCs possess a higher Shh expression as compared to nbMSCs.
Furthermore, CD[133.sup.+] NSCLC cells also exhibit CSC properties and secrete SHH ligand, and HH pathway inhibition in CD[133.sup.+] cells attenuated sphere formation, suggesting that the autocrine HH pathway is involved in CD[133.sup.+] CSC maintenance [87].
Outputs Selected inputs KH LL and SL EH ST and SL P ST and LL SHH ST and LL BPL ST and SL HW ST and LL Table 3.
As a result of the disposal, Orco will continue to hold some 2.6m SHH shares, equating to a 31.61% stake.
TICKETS: 01792 475715 TOMORROW Shh! Dance House, Wales Millennium Centre, Cardiff, 8pm A poignant piece of dance theatre, Shh!
But when all the blacks and Mexicans are dead, 'Shh, don't say anything.
dwd it s it's to a g"int we ho do we doM Jo pe Do aft wa shH sa Mc pe or JpDaws " McCall insisted ref John Beaton got the penalty decision for Dons' third goal wrong after Stephen McManus was penalised for shirt pulling.
In the high-payoff game (SHH), all payoffs are gains, so neither type of loss avoidance will have an effect on behavior.