SHH

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SHH

A gene on chromosome 7q36 that encodes a protein central in early embryonic patterning and the key inductive signal in patterning of the anterior-posterior limb axis, the ventral somites and the ventral neural tube.

Molecular pathology
Defects in SHH or in its signalling pathway cause holoprosencephaly, VACTERL syndrome; mutation upstream of SHH disrupts limb patterning and can result in preaxial polydactyly.

References in periodicals archive ?

Flecha blanca indica capa interna del iris inmunopositiva y fecha roja indica capa externa del iris negativa a Shh. C.

Embryo-fetal Development of Iris: Immunohistochemestry of Morphogen Shh/Desarrollo Embriofetal del Iris: Inmunotincion del Morfogeno Shh

Caption: Figure 1: (a) Subject-matched ntMSCs possess a higher Shh expression as compared to nbMSCs.

Human Neonatal Thymus Mesenchymal Stem Cells Promote Neovascularization and Cardiac Regeneration

Furthermore, CD[133.sup.+] NSCLC cells also exhibit CSC properties and secrete SHH ligand, and HH pathway inhibition in CD[133.sup.+] cells attenuated sphere formation, suggesting that the autocrine HH pathway is involved in CD[133.sup.+] CSC maintenance [87].

The Hedgehog Signaling Networks in Lung Cancer: The Mechanisms and Roles in Tumor Progression and Implications for Cancer Therapy

Outputs Selected inputs KH LL and SL EH ST and SL P ST and LL SHH ST and LL BPL ST and SL HW ST and LL Table 3.

Regression models for predicting anthropometric measurements of students needed for ergonomics school furniture design

Inhibition of Shh and PI3K/Akt Signaling Pathways by TMT in N2a Cells.

Lycium barbarum Polysaccharides Protect against Trimethyltin Chloride-Induced Apoptosis via Sonic Hedgehog and PI3K/Akt Signaling Pathways in Mouse Neuro-2a Cells

As a result of the disposal, Orco will continue to hold some 2.6m SHH shares, equating to a 31.61% stake.

Orco Property Group trims Suncani Hvar holding

This state of affairs was deemed unsustainable by SHH and in December 2010 the airline was sold to Eastern Airways.

Pondering plymouth: while many airports have opponents who would like to see them closed down, plymouth city airport in the uk is probably unique in that it has closed, but has a supporters' group that wants to re-open it. maurice wickstead reports

TICKETS: 01792 475715 TOMORROW Shh! Dance House, Wales Millennium Centre, Cardiff, 8pm A poignant piece of dance theatre, Shh!

7 worth going out for

But when all the blacks and Mexicans are dead, 'Shh, don't say anything.

Saints & sinners: who's watching your back and who's putting a knife in it

dwd it s it's to a g"int we ho do we doM Jo pe Do aft wa shH sa Mc pe or JpDaws " McCall insisted ref John Beaton got the penalty decision for Dons' third goal wrong after Stephen McManus was penalised for shirt pulling.

We won't lie down

In the ZPA, the key mediator is Sonic Hedghog (Shh).

Macrodactyly with polysyndactyly of distal phalanx of left second toe--a rare case report and its embryological review'

In the high-payoff game (SHH), all payoffs are gains, so neither type of loss avoidance will have an effect on behavior.

Payoff levels, loss avoidance, and equilibrium selection in games with multiple equilibria: an experimental study