PLAG1

(redirected from SGPA)
Also found in: Acronyms.

PLAG1

A gene on chromosome 8q12 that encodes PLAG1, a zinc finger transcription factor that is consistently rearranged in pleomorphic adenomas of the salivary gland. PLAG1 activation results in upregulation of IGFII, leading to uncontrolled cell proliferation in cultured cells; other genes upregulated by PLAG1 include CRLF1, CRABP2, CRIP2 and PIGF.

Molecular pathology
PLAG1 overexpression occurs in pleomorphic adenomas of the salivary gland, lipoblastoma and hepatoblastoma, and co-operates with CBFB-MYH11, a fusion gene in myeloid leukaemia.
References in periodicals archive ?
Chart 1: Per capita SGPA comparison: UE, USA, Brazil, China, 2005-2010, in national currencies.
Chart 2: SGPA comparison: UE, USA, Brazil, China, 2005-2010, in $billions.
farm support mostly includes direct subsidies for farmers' living standards (64 percent of SGPA in 2010), especially incorporating the Single Payment Schemes (SPSs), which account for 47 percent of all farm support paid in 2010.
Tenders are invited for Development including Pathway Retention tank and Land scaping plinth Protection and external Lighting at SGPA Campus Bhadbada road Bhopal
of Phoenix, designed by MCG Architecture of Beverly Hills, with SGPA Architecture and Planning of San Diego serving as the executive architect.