SF3B14

SF3B14

A gene on chromosome 2p23.3 that encodes a 14-kDa subunit of the splicing factor SF3B, which is required for pre-mRNA splicing. SF3B14 directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing, enters the (major) spliceosome, and associates with the pre-mRNA branch site as part of the U2 or, in the minor spliceosome, as part of the 1U11/U12 snRNP complex; it thus may facilitate the interaction of these snRNPs with the branch sites of U2 or U12.
References in classic literature ?
I had a theory that the gravitation of refraction, being subsidiary to atmospheric compensation, the refrangibility of the earth's surface would emphasize this effect in regions where great mountain ranges occur, and possibly so even-handed impact the odic and idyllic forces together, the one upon the other, as to prevent the moon from rising higher than 12,200 feet above sea-level.
And it continued to believe this until one of its subsidiary companies--the Gold and Stock--reported that several of its machines had been superseded by telephones.
Besides, I use subsidiary reservoirs only to attain a mean depth of 750 to 1,000 fathoms, and that with a view of managing my machines.
Dramatic action, therefore, is not with a view to the representation of character: character comes in as subsidiary to the actions.
The reason was that I had become mercifully engrossed in one of the subsidiary problems: whether it would be better to drop from the window or to trust to the creaking stairs.
But now that Lady Greystoke had disappeared, though he still looked toward the east for hope, his chances were lessened, and another, subsidiary design completely dashed.
Thus what was originally a false opinion as to the object of a desire acquires a certain truth: the false opinion generates a secondary subsidiary desire, which nevertheless becomes real.
Jasper as occupying the gatehouse, of which on the other side of the gateway, the Verger's hole-in-the-wall was an appanage or subsidiary part.