SERPINI2

SERPINI2

A gene on chromosome 3q26 that encodes a member of the serpin superfamily of serine proteinase inhibitors, which play key roles in regulating a variety of processes, including coagulation, fibrinolysis, development, malignancy and inflammation. SERPINI2 may have a role in a growth control, possibly via growth-suppressing pathway, which, when awry, has been linked to pancreatic carcinogenesis.
References in periodicals archive ?
In heifers, expression analysis of 40 candidate genes chosen by RNA-Seq resulted in dynamic, significantly regulated genes with extreme fold regulation values, ranging from 5-fold downregulation (APOA4) up to 82-fold up-regulation (SerpinI2).