SERPINB9

SERPINB9

A gene on chromosome 6p25 that encodes a member of the serine protease inhibitor (serpin) family that participates in a variety of cellular processes, such as coagulation, fibrinolysis, complement fixation, matrix remodeling and apoptosis. SERPINB9 inhibits granzyme B.
References in periodicals archive ?
Four genes with differential CpG methylation were identified: kelch-like family member 35 (KLHL35), calponin 2 (CNN2), serpin peptidase inhibitor clade B (ovalbumin) member 9 (SERPINB9), and adenylate cyclase 10 pseudogene 1 (ADCY10P1) [47].
Mutation Syndrome TAAD AAA FBN1 [5-8] Marfan + TGFBR1 [9], TGFBR2 [9,10] Loeys-Dietz + COL3A1 [11-14] Ehlers-Danlos + +/- TGFBR2, MYH11 [15,16], ACTA2 [17,18] Familial TAAD + LOX [19], MAT2A [20], SMAD3 [21, 22] PKD1 [23, 24], PKD2 [24] ADPKD + +/- NF1 [25-27] NF1 + +/- FBLN5 [28-30] + ELN [14] Williams + MMP2 [31], MMP9 [32], MMP12 [33] +/- MMP3 [34, 35] + TIMP1 [14] + LDLR1 [36, 37] + APOE E3/E3 [38] + PTPN11 [39-41] Noonan + MTHFR C677T [42-44] + ALOX15 [45, 46] + CNN2 [47] + SERPINB9 [47] + ADCY10P1 [47] + miR-21 [48], miR-146a [48] + miR-29b [49, 50] + +